

🚀 One treatment. Zero hassle. Total lice freedom.
RID One & Done is a prescription-strength ivermectin lotion that eradicates head lice, super lice, and nits with a single 10-minute application. Clinically proven and pediatrician recommended, it requires no nit combing and is safe for children as young as 6 months, making it the ultimate fast and effective solution for modern families battling resistant lice.




| ASIN | B0DTN81GNC |
| Best Sellers Rank | #4,448 in Health & Household ( See Top 100 in Health & Household ) #1 in Lice Shampoos & Rinses |
| Customer Reviews | 4.5 4.5 out of 5 stars (582) |
| Date First Available | January 22, 2025 |
| Manufacturer | Oystershell Consumer Health, Inc. |
| Product Dimensions | 2.44 x 1.57 x 6.69 inches; 4 ounces |
D**G
Simple to use and works fast!
I found myself having to purchase this for my little one and didn’t think that just one would do the trick, to my surprise it really did take care of all cycles of the lice. It was really simple to use and it had clear instructions. The smell wasn’t strong and it didn’t bother me or my child at all. We were done within an hour with the whole process and the rinse off. My child did not complain that it burned or have any reaction to the formula, you can always test a small spot beforehand to verify. The tube came with enough to do two people but is recommended just for one. I would recommend this to anyone in need.
M**N
GREAT product, just a bit pricey.
This stuff is AWESOME! This was the 2nd time we've had to deal with my daughter having lice. The first time was 5 years ago (when she was 5) & thankfully we had already cut her hair (that was down to the back of her knees) before that, otherwise I probably would've shaved her head. We spent MONTHS trying to get rid of the lice. Finally, a little bottle of regular Dawn dish soap with some tee tree oil a friend told me about worked. This time, it didn't seem to work. We saw this & decided to give it a try. So happy we did! There was a little left over after using it on my daughter's hair, so my wife used it on her's, but ended up needing more. I'm happy to say that it worked for both of them & there were A LOT less tears this time around than 5 years ago! We also loved the fact that it wasn't messy. I read a review that someone said it was really messy. Not sure what they did, because this was NOT messy. My only issue is the price. It's sad that it costs so much. Not everyone can afford a great product that actually works when it costs so much. I'd actually like to buy several tubes to have on hand when my daughter or grandkids get lice, but can't afford to do that right now.
N**A
Effective… ivermectin is the key
As someone who works in science, I tend to be skeptical of flashy claims and “miracle” lice products. But RID One & Done genuinely impressed me. It’s straightforward, it works as intended, and it doesn’t come with the price tag of some of the trendier options. What I appreciated most is how practical the whole process is. Following up after a bit of time helps ensure you’re not dealing with any late‑hatching stragglers, and being gentle with a nit comb makes a world of difference — especially for anyone with hair that doesn’t love aggressive detangling. After trying the expensive treatments on the market, I can confidently say I won’t be wasting money on those again. This one gets the job done without the drama. The only down side is that it’s very thick… but I will take that over paying 40 bucks for something that doesn’t work any day. A bottle was enough for my son with medium length and lots of hair, and me with long hair.
B**Z
Once and Done... nope. Not true.
Looking back It did work! Five stars It hasn't worked yet. I think it has helped some, but I just bought a different product to use to finish the job, I hope. It's been a week and the Lice are NOT gone. BTW, I did remove all bedding and washed and dried using very high heat. I will now use the additional treatment I bought at the store. I think If I had bought two or more of these Once and Done treatments it would have worked as I did see improvement after two or three days.
T**A
Perfect for long thick hair!
This lice treatment truly works—and it got the job done in just one application. We used it on long, thick, curly hair, which would normally take hours with a traditional lice pick comb, and the results were impressive. The process was much quicker and far less stressful, with no endless combing required. It saved so much time and frustration while still being extremely effective. Highly recommend this product for anyone dealing with lice, especially if thick or curly hair makes traditional methods feel impossible.
S**E
Worked well
It worked, got rid of the lice in one application
V**Y
SUPER LICE ARE IMMUNE
This stuff doesn't work because lice have become immune to these treatments. We now have SUPER LICE! The absolute best instruction is at My Lice Advice and the solution is inexpensive and effective in just one day. She is thorough and works with school systems to treat lice. She also tells you how to clean your home. Again, one and done! My husband and I think we got lice from our bargain hair salon where they cut a lot of kids hair but just not sure. We used 3 boxes of this stuff plus used the proper lice comb (essential) and we are still fighting lice. Tomorrow we do it per My Lice Advice and it truly should be one and done! I am not getting a commission from My Lice Advice; just want everyone to save their money and go straight to the expert for a safe, effective solution.
C**S
It does work
Yes it does work, I would suggest combing even though it says not to! And I would suggest using a second time a few days after first treatment
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