--- product_id: 10236677 title: "- Dr. Denese SkinScience HydroShield Retinol Serum for Face 4 oz – Dermatologist Tested Hydrating Serum, Contains Retinol and Ceramides for Deep Moisture - Cruelty Free" brand: "dr. denese" price: "$U10561" currency: UYU in_stock: true url: https://www.desertcart.uy/products/10236677-dr-denese-skinscience-hydroshield-retinol-serum-for-face-4-oz store_origin: UY region: Uruguay --- # Cruelty-free formula 184% hydration boost Clinically proven tech - Dr. Denese SkinScience HydroShield Retinol Serum for Face 4 oz – Dermatologist Tested Hydrating Serum, Contains Retinol and Ceramides for Deep Moisture - Cruelty Free **Brand:** dr. denese **Price:** $U10561 **Availability:** ✅ In Stock ## Summary > ✨ Unlock Your Glow with HydroShield! ## Quick Answers - **What is this?** - Dr. Denese SkinScience HydroShield Retinol Serum for Face 4 oz – Dermatologist Tested Hydrating Serum, Contains Retinol and Ceramides for Deep Moisture - Cruelty Free by dr. denese - **How much does it cost?** $U10561 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.uy](https://www.desertcart.uy/products/10236677-dr-denese-skinscience-hydroshield-retinol-serum-for-face-4-oz) ## Best For - dr. denese enthusiasts ## Why This Product - Trusted dr. denese brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Rapid Results:** See a remarkable 184% increase in hydration in just 15 minutes! - • **Skin-Identical Lipids:** Replenish your skin's natural barrier with essential fatty acids and ceramides. - • **All Skin Types Welcome:** Perfect for everyone, from dry to oily skin, ensuring no one is left behind. - • **Hydroshield Technology:** Harness years of medical research for advanced hydration and skin rejuvenation. - • **Unlock Youthful Radiance:** Experience a supercharged serum that locks in moisture and reduces the appearance of wrinkles. ## Overview Dr. Denese SkinScience HydroShield Ultra Moisturizing Face Serum is a clinically proven, award-winning serum designed to lock in moisture and reduce the appearance of wrinkles. Infused with retinol and ceramides, it enhances skin hydration and elasticity while being suitable for all skin types. This cruelty-free product is backed by rigorous safety testing and is formulated with a focus on high-quality ingredients. ## Description SkinScience HydroShield Ultra Moisturizing Face Serum 4 oz – Retinol & Ceramide Formula for Deep Moisture, Smooth Radiant Skin, Fine Line Care – Dermatologist-Tested & Cruelty-Free ## Features - ADVANCED HYDRATION - Our Hydroshield Serum is based on years of medical research that identified a unique and proprietary technology that we named Hydroshield Technology. Clinically proven and a multiple QVC Customer Choice Award winner, a supercharged hydrating serum that locks in moisture to drastically reduce the look of dry lines and wrinkles and helps plump the appearance of the skin. - PROVIDES SKIN IDENTICAL LIPIDS - As we age, skin lipids decline, leaving the skin dry and line prone. Our proprietary blend supplies a balance of skin identical lipids, as it is extremely important to build lipid barriers as much as possible to protect what lies within. Also contains ceramides and essential fatty acids to help the skin lipid barrier to function at a much younger level. Hydration and moisture is locked into the skin, to rapidly improve the appearance of dry lines and wrinkles. - LOCKS IN MOISTURE - Contains retinol which helps to firm the skin, reduce the look of fine lines and wrinkles and stimulate collagen production. Working to smooth lines and wrinkles and improve tone and elasticity. Ceramides are added to help mimic your skin's lipid barrier, prevent water loss, improve suppleness and skin texture while calming the skin. Studies have shown 184% increase in skin hydration after 15 minutes! - BENEFICIAL FOR ALL SKIN TYPES - Suitable for any skin types from dry to normal. Those with oily or combination skin may want to target their dry or rough spots. Can be used in the morning and evening, applied to clean face before your day cream or night cream. Let the serum penetrate for a few minutes, until it turns matte. If you have oily or normal skin, apply only around the eyes, cheeks and neck. Never neglect the eye area, even if you are oily, the eye area skin is almost always dry. - TESTED, TRUSTED QUALITY - We pride ourselves on quality of our products and perform product safety testing by third-party, independent, certified testing laboratories. We do not believe in animal testing and all of Dr. Denese products are manufactured under FDA-mandated procedures. The key is to use the RIGHT ingredients in the RIGHT percentages, because with skin care everything is in the percentages. Our goal is to give you an exceptionally high percentage of the key ingredients. ## Product Details - **Skin Type:** Oily, Combination, Dry, Normal - **Product Benefits:** Hydrating - **Use for:** Face - **Scent:** Aloe - **Special Ingredients:** retinol, collagen, ceramides ## Images ![- Dr. Denese SkinScience HydroShield Retinol Serum for Face 4 oz – Dermatologist Tested Hydrating Serum, Contains Retinol and Ceramides for Deep Moisture - Cruelty Free - Image 1](https://m.media-amazon.com/images/I/71AnQ+eo+CL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: Do you really have to leave it on for 7 min before applying other products?** A: Yes, you really should. Matter-of-fact, I leave it on to dry even longer. 10 minutes or more--when I'm not in a hurry. It seems to be a silicone-based moisturizer, so let it dry for a few minutes before you put on the night cream, or the day spf cream. I like the stuff. It moisturizes well. Yes, follow the directions. **Q: What are the ingredients? A list of ingredients should be listed on every cosmetic product.** A: I found this info on another website that sells Dr. Denese products: Ingredients: Dimethicone, Glycine Soja (Soybean) Seed Extract, Ceramide II, Retinol, Tocopherol, Linoleic Acid, Linolenic Acid, Ethylhexyl Cocoate, Lecithin, Glycolipids, Phenoxyethanol. **Q: I didn’t get any instructions other than what is on the box side. How much do I use? All over the face?** A: I use it all over my face except on my eyelids. I usually use one squirt. Leave it on your face for a few minutes and then massage it in. I use another moisturizer on top of it but it’s not necessary. **Q: What percentage is the retinol?** A: That's proprietary. They're probably not going to divulge that information. It's probably not much. I use a prescription retinol cream, and it's only .025%. Yeah, that's not a typo: .025%. Tretinoin cream. ## Frequently Bought Together - Dr. Denese SkinScience HydroShield Ultra Moisturizing Face Serum Locks In Moisture with Retinol & Ceramides - Reduce Appearance of Wrinkles, Increased Hydration & Tightness - Cruelty-Free - 4oz - Dr. Denese SkinScience HydroShield Hydrating Dream Cream Advanced Hydration with Retinol, Peptides & Cermides To Help Maintain Moisture Tone & Elasticity - Reduce the Look of Fine Lines - 3.4oz - Dr. Denese SkinScience Advanced Firming Facial Pads Exfoliator & Deep Pore Face Cleanser, Toner & Skin Care Glycolic Acid, Peptides & Aloe - Vegan, Paraben-Free, Cruelty-Free - 100 Count --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.uy/products/10236677-dr-denese-skinscience-hydroshield-retinol-serum-for-face-4-oz](https://www.desertcart.uy/products/10236677-dr-denese-skinscience-hydroshield-retinol-serum-for-face-4-oz) --- *Product available on Desertcart Uruguay* *Store origin: UY* *Last updated: 2026-04-24*